A gauge of Asian stocks outside Japan climbed, headed for its biggest weekly gain in more than four months, as health-care and information technology companies advanced. Stocks in Tokyo tumbled after the yen strengthened.

Nikkei 225 14,313.03 -221.71 -1.53%

S&P/ASX 200 5,356.26 +48.15 +0.91%

Shanghai Composite 2,115.85 +17.45 +0.83%

Shandong Weigao Group Medical Polymer Co. jumped 5.3 percent in Hong Kong to lead health-care companies higher.

Tencent Holdings Ltd. rose to a record after Jefferies Hong Kong Ltd. boosted its target price on Asia’s largest Internet company by market value.

Kirin Holdings Co. fell 9.2 percent after the Japanese beverage maker forecast profit that missed analysts’ estimates.