Major U.S. stock-indexes little changed on Monday, helped by gains in materials and energy stocks, but trading was subdued in the run-up to Thursday's Thanksgiving holiday.

The two stocks were the biggest drags on the S&P 500, while Pfizer was the biggest drag on the Dow. Analysts expressed concerns about what were seen as the low synergies from the deal, its complexity, antitrust issues and a possible delay in Pfizer's plan to split in two companies.

Most of Dow stocks in negative area (18 of 30). Top looser - Pfizer Inc. (PFE, -2.14%). Top gainer - The Coca-Cola Company (KO +1.47%).

Almost all of S&P index sectors also in positive area. Top looser - Utilities (-0.5%). Top gainer - Conglomerates (+1,0%).

At the moment:

Dow 17787.00 -14.00 -0.08%

S&P 500 2089.25 +0.50 +0.02%

Nasdaq 100 4688.50 -1.00 -0.02%

Oil 42.29 +0.39 +0.93%

Gold 1068.90 -7.40 -0.69%

U.S. 10yr 2.26 +0.00