Major U.S. stock-indexes fell to session lows in early afternoon trading on Wednesday as the outcome of the negotiations between Greece and its international creditors remained up in the air. Creditors demanded sweeping changes to Greek Prime Minister Alexis Tsipras' tax and reforms proposals, adding fresh uncertainty to talks aimed at unlocking aid to avert a debt default next week. Greece needs fresh funds to avoid defaulting on a $1.8 billion debt repayment to the IMF on June 30.

Almost all Dow stocks trading in negative area (27 of 30). Top looser - E. I. du Pont de Nemours and Company (HD, -3.08%). Top gainer - Apple Inc. (AAPL, +1.72).

S&P index sectors also in negative area. Top looser - Healthcare (-0.7%).

At the moment:

Dow 17942.00 -125.00 -0.69%

S&P 500 2106.75 -9.75 -0.46%

Nasdaq 100 4532.50 -8.75 -0.19%

10-year yield 2.40% -0.01

Oil 60.11 -0.90 -1.48%

Gold 1172.60 -4.00 -0.34%