Major U.S. stock-indexes started the fourth quarter on a weak note as healthcare stocks fell and Deutsche Bank's (DB) travails weighed on financials. The German lender is working to reach a settlement with U.S. authorities who have demanded a fine of up to $14 billion for mis-selling mortgage-baked securities.

Most of Dow stocks in negative area (24 of 30). Top gainer - E. I. du Pont de Nemours and Company (DD, +2.36%). Top loser - The Travelers Companies, Inc. (TRV, -1.53%).

All S&P sectors also in negative area. Top loser - Utilities (-1.0%).

At the moment:

Dow 18145.00 -74.00 -0.41%

S&P 500 2150.75 -9.75 -0.45%

Nasdaq 100 4849.50 -20.75 -0.43%

Oil 48.56 +0.32 +0.66%

Gold 1313.20 -3.90 -0.30%

U.S. 10yr 1.62 +0.01