European stocks slid, posting their longest losing streak in five months, as European Central Bank President Mario Draghi said that financial-market developments and low domestic demand may hurt the euro area’s economy.

The Stoxx Europe 600 Index lost 0.9 percent to 314.47 at 4:30 p.m. in London. The equity benchmark has gained 12 percent this year as central banks around the world pledged to keep interest rates low for a prolonged period of time. The Stoxx 600 slipped 0.6 percent yesterday as better-than-expected U.S. jobs data fueled concern that the Federal Reserve will reduce its monthly bond purchases sooner than forecast.

Draghi said that increased commodity prices, weaker domestic demand and slow export growth all posed downside risks to the outlook for the euro area’s economy. He also identified failure to implement structural reforms by the governments of the 18 countries that use the single currency as a risk.

“Developments in global money- and financial-market conditions and related uncertainties may have the potential to negatively affect economic conditions,” Draghi said.

ECB officials kept the main refinancing rate unchanged at 0.25 percent as predicted by every economist. The central bank for the euro area lowered interest rates to 0.25 percent from 0.5 percent last month.

In the U.K., the Bank of England left its key interest rate at a record low of 0.5 percent, in line with its own guidance on rates. The Office for Budget Responsibility raised its growth forecast for 2013 to 1.4 percent from the 0.6 percent that it predicted in March. The agency charged with making independent projections on the British economy also said that gross domestic product will climb 2.4 percent in 2014. It had projected growth next year of 1.8 percent.

Tomorrow’s U.S. payrolls report may help investors gauge the outlook for stimulus in the world’s largest economy. The Federal Open Market Committee meets on Dec. 17-18 to consider changes to its $85 billion of monthly bond buying. Officials said at their Oct. 29-30 meeting that they may slow their asset purchases if the economy improves as forecast.

FTSE 100 6,498.33 -11.64 -0.18% CAC 40 4,099.91 -48.61 -1.17% DAX 9,084.95 -55.68 -0.61%

FLSmidth declined 1.9 percent to 268 kroner. The company lowered its forecast earnings before interest, taxes and amortization ">Vienna Insurance dropped 5.6 percent to 34.43 euros. An unidentified investor offered 83 million euros of shares in the company. They were sold at 34.10 euros apiece, according to two people with knowledge of the deal.

Metro AG retreated 4.9 percent to 34.23 euros, its biggest slide since June. Morgan Stanley lowered Germany’s biggest retailer to equal weight, the equivalent of hold, from overweight. The brokerage cited the lack of near-term catalysts to support further gains in the share price. Metro has rallied 63 percent so far this year.

AZ Electronic Materials rallied 50 percent to 395 pence. Merck agreed to pay 403.5 pence a share for the Luxembourg-based company, it said in a statement. The acquisition will enable the German drugmaker’s chemicals division to expand into new markets. Merck rallied 5.9 percent to 131.70 euros.

Remy Cointreau SA advanced 2.6 percent to 61.97 euros after the maker of Remy Martin cognac said its board has authorized a buyback of as many as 2.5 million shares. The drinks company will cancel the shares that it purchases.

U.S. stock-index futures erased earlier gains, after data showing faster-than-forecast economic growth fueled speculation the Federal Reserve will curb stimulus spending.

Global markets:

Nikkei 15,177.49 -230.45 -1.50 %

Hang Seng 23,712.57 -16.13 -0.07 %

Shanghai Composite 2,247.06 -4.70 -0.21 %

FTSE 6,496.63 -13.34 -0.20 %

CAC 4,126.43 -22.09 -0.53 %

DAX 9,114.43 -26.20 -0.29 %

Crude oil $97.25 (+0.05%).

Gold $1224.80 (-1.80%).

European stocks were little changed, following a four-day decline, as investors awaited interest-rate decisions from the European Central Bank and the Bank of England. U.S. index futures fluctuated, while Asian shares fell.

ECB President Mario Draghi releases inflation and growth projections today at the central bank’s first meeting since the Governing Council cut interest rates to a record low.

Officials will keep the benchmark rate unchanged this time, according to every economist in a Bloomberg News survey. Policy makers will announce their decision at 1:45 p.m. in Frankfurt. Draghi will host a press conference, setting out the forecasts, 45 minutes later.

In the U.K., Chancellor of the Exchequer George Osborne delivers his Autumn Statement today. The Office for Budget Responsibility will also raise its growth forecast for 2013 to 1.4 percent from the 0.6 percent that it predicted in March, according to the median estimate in a Bloomberg survey.

The Bank of England will announce its interest-rate decision at 12 p.m. in London. The central bank will leave its benchmark rate at a record low and its bond-buying program unchanged, separate surveys show.

AZ Electronic Materials rallied 52 percent to 398.5 pence. Merck agreed to pay 403.5 pence a share for the Luxembourg-based company, it said in a statement. The acquisition will enable the German drugmaker’s chemicals division to expand into new markets. Merck climbed 3.5 percent to 128.75 euros, the highest price since its initial public offering in October 1995.

Remy Cointreau SA advanced 3.4 percent to 62.46 euros after the maker of Remy Martin cognac said its board has authorized a buyback of as many as 2.5 million shares. The drinks company will cancel the shares that it purchases.

FLSmidth declined 1.1 percent to 270.30 kroner. The company lowered its forecast earnings before interest, taxes and amortization ">FTSE 100 6,509.13 -0.84 -0.01%

CAC 40 4,145.33 -3.19 -0.08%

DAX 9,151.59 +10.96 +0.12%

Asian stocks fell, with the regional benchmark index heading for a three-week low, amid concern signs of improvement in the U.S. jobs market will prompt the Federal Reserve to bring forward cuts to stimulus.

Nikkei 225 15,177.49 -230.45 -1.50%

S&P/ASX 200 5,197.96 -75.79 -1.44%

Shanghai Composite 2,247.06 -4.70 -0.21%

Nissan Motor Co., a Japanese carmaker that gets 34 percent of its revenue in North America, dropped 3.5 percent.

Qantas Airways Ltd. tumbled 11 percent after Australia’s largest carrier announced job cuts and forecast a A$300m ($271 million) first-half loss amid competition.

Standard Chartered Plc sank 4.8 percent in Hong Kong after the U.K. lender said full-year operating profit at its consumer-banking unit will drop at least 10 percent, hurt by its Korean business.

Nikkei 225 15,407.94 -341.72 -2.17%

Hang Seng 23,756.84 -153.63 -0.64%

S&P/ASX 200 5,273.8 +17.73 +0.34%

Shanghai Composite 2,252.38 +29.71 +1.34%

FTSE 100 6,509.97 -22.46 -0.34%

CAC 40 4,148.52 -23.92 -0.57%

DAX 9,140.63 -82.77 -0.90%

Dow -23.95 15,890.67 -0.15%

Nasdaq +0.8 4,038.00 +0.02%

S&P -2.29 1,792.86 -0.13%